What is the best treatment for chondrosarcoma?

Treatment

  • Surgery. The goal of surgery for chondrosarcoma is to remove the cancer and a margin of healthy tissue around it.
  • Radiation therapy. Radiation therapy uses high-powered energy beams from sources such as X-rays and protons to kill cancer cells.
  • Chemotherapy.
  • What you can do.
  • What to expect from your doctor.

Is Chemotherapy Effective for chondrosarcoma?

Chemotherapy (chemo) is not usually very effective against chondrosarcoma cells, so it’s not often used to treat this type of cancer.

How long can you live with chondrosarcoma?

Chondrosarcoma

SEER stage 5-year relative survival rate
Localized 91%
Regional 75%
Distant 23%
All SEER stages combined 79%

Can you survive chondrosarcoma?

The 5-year survival rate for chondrosarcoma is 75.2%, which is much higher than that of osteosarcoma and Ewing sarcoma 3. Tumor size, grade, stage, local recurrence, metastasis at presentation, systemic treatment, and radiotherapy are all associated with the prognosis of chondrosarcoma 4-7.

How serious is chondrosarcoma?

Most chondrosarcomas grow slowly and may not cause many signs and symptoms at first. Some rare types grow rapidly and have a high risk of spreading to other areas of the body, which can make these cancers difficult to treat.

What are the stages of chondrosarcoma?

The Enneking staging system for musculoskeletal sarcomas is applicable to chondrosarcomas, as follows : Stage I (low-grade tumor) – Stage I-A, intracompartmental; stage I-B, extracompartmental. Stage II (high-grade tumor) – Stage II-A, intracompartmental; stage II-B, extracompartmental. Stage III (distant metastasis)

Why is chondrosarcoma chemo resistant?

There are reasons why chondrosarcomas are chemoresistant; tissue access of chemotherapeutic drugs is more difficult in chondrosarcomas than in vascularized cancers as the drugs have to diffuse over a long distance to reach tumour cells; chondrosarcomas have high expression of the multidrug resistance–associated protein …

Is chondrosarcoma always malignant?

Chondrosarcoma is a malignant type of bone cancer that primarily affects the cartilage cells of the femur (thighbone), arm, pelvis, knee, and spine. Although less frequent, other areas (such as the ribs) may be affected. Chondrosarcoma is the second most common type of primary bone cancer.

Does chondrosarcoma spread fast?

Chondrosarcoma tends to grow slowly, so it might not cause signs and symptoms at first. When they occur, signs and symptoms of chondrosarcoma may include: Increasing pain. A growing lump or area of swelling.

Is chondrosarcoma malignant?

Chondrosarcomas are malignant cartilaginous neoplasms with diverse morphological features and clinical behavior. They account for about 20 percent of all primary malignant tumors of the bone and usually arise in the pelvis or long bones.

What is advanced chondrosarcoma?

Chondrosarcoma is a malignant tumor of bones, characterized by the production of cartilage matrix. Due to lack of effective treatment for advanced disease, the clinical management of chondrosarcomas is exceptionally challenging.

Why is chondrosarcoma resistant to chemotherapy?