What is pre-analytical laboratory procedure?

Preanalytical phase comprises of test selection, patient identification, collection of the sample, handling of the sample, sorting out, pipetting and centrifugation (2, 3). Negligence in any of these steps can lead to erroneous results attributed to preanalytical phase.

Which of the following is an example of a pre-analytical error?

The most commonly reported types of pre-analytical error are: a) missing sample and/or test request, b) wrong or missing identification, c) contamination from infusion route, d) haemolysed, clotted, and insufficient samples, e) inappropriate containers, f) inappropriate blood to anticoagulant ratio, and g) …

What are preanalytical variables discuss it with an example?

Under the broad umbrella of the preanalytical phase can be included specimen collection, handling and processing variables, physiological variables such as the effect of lifestyle, age, gender, pregnancy and menstruation and endogenous variables such as drugs and circulating antibodies.

What are 3 phases of laboratory testing?

Total testing process in the laboratory is a cyclical process divided into three phases: preanalytical, analytical and postanalytical.

What are pre-analytical errors in laboratory?

The preanalytical errors refer to all of the inappropriate performances before the specimens are measured by analyzers, such as improper sample collection, transport delays, illegible handwriting on requisition, and so on.

Why is pre-analytical phase important?

The preanalytic phase is an important component of total laboratory quality. A wide range of variables that affect the result for a patient from whom a specimen of blood or body fluid has been collected, including the procedure for collection, handling, and processing before analysis, constitute the preanalytic phase.

What is the most common laboratory error in pre-analytical process?

Hemolysis. Hemolysis is caused by cell blood lysis and is considered the most frequent preanalytical error. Hemolysis is also the most common cause of sample rejection by the central laboratory.

What are the preanalytical errors?

What is the most common source of pre-analytical error in CK determination?

Hemolysis. Hemolysis is caused by cell blood lysis and is considered the most frequent preanalytical error.

What is the laboratory process?

Lab procedures are detailed documents, checklists or guidelines that instruct you how to safely carry out an action in a laboratory environment. The key here is to remember that a lab process tells your team how to do something (create a compound, carry out a reaction, etc).

What is a laboratory workflow?

A laboratory workflow is a set of procedural rules used to manage and coordinate tasks between people and systems in the lab. Lab workflows for sample management ensure that all steps and requirements in a defined process are correctly.

What are examples of analytical errors?

Some examples of analytical errors include equipment malfunction, procedures (i.e., standard operating procedures and assay instructions) not followed, undetected failure of quality control, sample mixups, and test interference.

What does pre-analytical mean?

preanalytical (not comparable) Describing any procedure that takes place before an analysis. Describing any variable whose value can affect the outcome of a subsequent analysis.

How can pre-analytical errors be prevented in the laboratory?

“Other measures for avoiding preanalytical errors that have proven successful are: never accept an unlabelled sample. Never allow unlabelled or mislabeled samples to be relabeled, if recollection is feasible.” “Document relabeling must be approved by an attending physician, with results footnoted.

How do you overcome pre-analytical errors?

Steps labs can take: minimizing pre-analytical errors

  1. Phlebotomy education.
  2. Using appropriate technology.
  3. Choosing appropriate products.
  4. Adhering to standard guidelines.
  5. Developing clear, written procedures.
  6. Validating any new instrument or procedure.
  7. Monitoring quality indicators in the lab.

How can pre-analytical errors be prevented?

What are basic laboratory techniques?


  • Extraction.
  • Drying Agents.

What are the three types of laboratories?

Company laboratories fall into three clear categories: research laboratories, development laboratories, and test laboratories. Research laboratories carry out both basic and applied research work.

What are the laboratory workflow phases?

Preanalytical phase. Selecting the appropriate test, obtaining the specimen, labeling it with the patient’s name, providing timely transport to the laboratory, registering receipt in the laboratory, and processing before testing. Analytical phase.

What is laboratory sample management?

A sample management software or Laboratory Information management System (LIMS) ensures the data security and accuracy of all the samples right from when they are received in the lab until they are processed, tested and shipped out.

What are pre-analytical errors in lab?

What is laboratory techniques and procedures?

Definition. Laboratory techniques and procedures are performed on patient specimens to detect biomarkers and diagnose diseases. Blood, urine, semen or tissue samples can be analysed using biochemical, microbiological and cytological methods.

What is the most essential laboratory technique?

Blotting Techniques

Blotting is the most common lab technique widely used in the field of cell & molecular biology.

What are the five types of laboratory?

Diagnostic laboratories. Diagnostic laboratories primarily run tests on clinical specimens such as urine, blood, triglycerides, or cholesterols.

  • Hospital laboratories.
  • National laboratories.
  • Clinical laboratories.
  • Research and university laboratories.
  • What are the laboratory methods?

    Laboratory Analytical Techniques

    • Chromatography Laboratory Analysis.
    • Spectroscopy Laboratory Analysis.
    • Mass Spectrometry.
    • Microscopy Laboratory Analysis.
    • Thermal Analysis and Testing.
    • Elemental Analysis Techniques.
    • Surface Analysis.