What is Penidure?

Penidure LA 12 Injection is an antibiotic used to treat a variety of bacterial infections. It is effective in treating sore throat and sexually transmitted diseases like Syphilis. This medicine is also used to prevent some bacterial infections such as Rheumatic fever.

Why is benzathine added to penicillin?

Benzathine and procaine salts of penicillin G are designed for depot intramuscular injections which are used to provide prolonged blood and tissue levels.

What is the difference between benzylpenicillin and benzathine penicillin?

Specifically it is used to treat strep throat, diphtheria, syphilis, and yaws. It is also used to prevent rheumatic fever. It is given by injection into a muscle.

Benzathine benzylpenicillin.

Combination of
Other names penicillin benzathine benzyl, benzathine penicillin, penicillin G benzathine, benethamine penicilline, benzylpenicillin benzathine

What is penicillin injection used for?

Penicillin G injection is used to treat and prevent certain infections caused by bacteria. Penicillin G injection is in a class of medications called penicillins. It works by killing bacteria that cause infections. Antibiotics such as penicillin G injection will not work for colds, flu, or other viral infections.

Why is Penidure injection given?

Penidure LA 12 Injection is an antibiotic that is used to treat upper respiratory tract infections and syphilis caused by susceptible bacteria. It is also used to prevent some infections such as rheumatic fever, and infection of the heart valves (bacterial endocarditis) in people with pre-existing heart disease.

Is Penidure injection painful?

The penicillin injections (long-acting benzathine penicillin G) are invariably painful because of the large volume that is injected, the viscosity and possibly the irritant nature of the solution.

How painful is benzathine penicillin?

Intramuscular (IM) Penicillin G Benzathine (PGB) is the cornerstone of the treatment of primary syphilis [1], but its administration is associated with sharp pain at the site of the injection that sometimes may be of severe intensity.

How long will penicillin last?

Official answer. Penicillin will be out of your system after your last dose in about 7.7 hours. Penicillin has an elimination half-life of approximately 1.4 hours or less.

What is another name for benzylpenicillin?

Benzylpenicillin, also known as penicillin G (PenG) or BENPEN, and in military slang “Peanut Butter Shot” is an antibiotic used to treat a number of bacterial infections. This includes pneumonia, strep throat, syphilis, necrotizing enterocolitis, diphtheria, gas gangrene, leptospirosis, cellulitis, and tetanus.

Why is it called penicillin G?

The two so-called natural penicillins are both produced biosynthetically from Penicillium chrysogenum by fermentation. Benzylpenicillin (penicillin G) is formed if phenylacetic acid is added to the culture medium and Phenoxymethylpenicillin (penicillin V) is formed when phenoxyacetic acid is added.

Is penicillin a good antibiotic?

Because penicillin became one of the most commonly used antibiotics in the world, many bacterial species have gained resistance against it. However, it is still useful for certain bacterial infections. Penicillin is a narrow-range antibiotic that covers gram-positive bacteria and some gram-negative bacteria.

What diseases does penicillin cure?

Penicillin is used to treat a variety of bacterial infections, including meningitis, pneumonia, gonorrhea, syphilis, and endocarditis.

Why is penicillin injection painful?

What are side effects of penicillin injections?


  • Abdominal or stomach cramps and pain (severe)
  • abdominal tenderness.
  • convulsions (seizures)
  • decreased amount of urine.
  • diarrhea (watery and severe), which may also be bloody.
  • mental depression.
  • nausea and vomiting.
  • pain at place of injection.

How long does penicillin last in your body?

by Drugs.com

Penicillin will be out of your system after your last dose in about 7.7 hours. Penicillin has an elimination half-life of approximately 1.4 hours or less. 5.5 x 1.4 hours = 7.7 hours for penicillin.

What are the side effects of penicillin injection?

Is 5 days of antibiotics enough?

Researchers from the CDC point out that, when antibiotics are deemed necessary for the treatment of acute bacterial sinusitis, the Infectious Diseases Society of America evidence-based clinical practice guidelines recommend 5 to 7 days of therapy for patients with a low risk of antibiotic resistance who have a …

What type of antibiotic is benzylpenicillin?

Pharmacotherapeutic group: Beta-lactamase sensitive penicillins. ATC code: J01 CE01. General Properties: Benzylpenicillin sodium is a beta-lactam antibiotic.

Is penicillin injection painful?

Is penicillin safe for liver?

Liver injury is extremely rare with ampicillin, and rare with benzylpenicillin (penicillin G) and phenoxymethylpenicillin (penicillin V). Amoxicillin has little hepatotoxic potential if administered alone (see hereunder for amoxicillin/clavulanate).

Can penicillin damage the liver?

Three distinct forms of liver injury can occur with the first generation penicillins: (1) transient, asymptomatic elevations in serum aminotransferase levels with prolonged high doses of parenteral penicillin, (2) minor liver injury associated with severe hypersensitivity reactions, and (3) idiosyncratic, delayed …

Is penicillin a steroid or antibiotic?

Penicillin is an antibiotic used to treat certain types of bacterial infections, such as pneumonia, meningitis, or strep throat. There are different types of penicillin with different mechanisms of action.

What are benefits of penicillin?

Penicillin prevents the bacteria from synthesizing peptidoglycan, a molecule in the cell wall that provides the wall with the strength it needs to survive in the human body. The drug greatly weakens the cell wall and causes bacteria to die, allowing a person to recover from a bacterial infection.

How long does a penicillin injection last?

After a 1.2 million unit injection, adults have detectable drug concentrations for 14 days, often longer. The medication is excreted by renal tubular excretion.

What is the most serious side effect of penicillin?

Penicillin is prescribed for treating various bacterial infections. Common signs and symptoms of penicillin allergy include hives, rash and itching. Severe reactions include anaphylaxis, a life-threatening condition that affects multiple body systems.