Can you have a reaction to a B12 injection?

Injection Site Reactions

Upon receiving the B12 injection, you may experience a skin reaction in or around the area in which the injection was placed. Pain, redness, and swelling may occur shortly after the procedure is complete. There may also be some irritation in the area, as well as a risk of infection.

What are symptoms of too much B12 injections?

There is no upper limit for the intake of vitamin B12 because the risk of toxicity or overdose is low. However, vitamin B12 shots may have other side effects.


  • pain, redness, or itching at the site of the injection.
  • mild diarrhea.
  • a swelling sensation in the body.
  • temporary itching of the skin.

Where is the best place to give a B12 injection?

The easiest site when self-administering an IM injection is the middle third of the vastus lateralis muscle of the thigh. Other options include the deltoid muscle of the upper arm and the dorsogluteal site on the bottom. This maybe useful if you have a carer or a family member willing to administer your injection.

Can B12 injections cause a rash?

Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects: mild diarrhea. itching. skin rash.

What does a B12 rash look like?

Vitamin B12 is essential for every cell in the human body (animals too), so it may seem strange, but some people are allergic to it and they can suffer either an acute or chronic itchy rash that can have small blisters containing a clear fluid, skin that is red, swollen, oozing, or peeling.

What are the side effects of vitamin B12 injections?

Vitamin B12 injections are generally considered to be very safe. They have no major side effects. However, in very rare cases, some people can experience side effects caused by allergic reactions or sensitivity ( 29 , 30 ). If you experience any side effects, speak with your doctor.

How long does it take for a B12 shot to wear off?

around 48 hours to 72 hours
Simply put, how long the B12 shot will last is different for everyone. Though it differs a bit from one person to another, the effects of B12 vitamins usually last around 48 hours to 72 hours after the initial injection.

What does a vitamin B12 rash look like?

Is B12 subcutaneous or intramuscular?

Vitamin B12 injections can be administered as an intramuscular or subcutaneous injection.

What size needle should be used for B12 injections?

Gather your B-12 medication vial, a 1 ml syringe and a 22- to 25-gauge needle that’s 1 to 1 1/2 inches long. The larger-gauge needle is finer than the 22 and will provide the most comfort during the injection. Also, the needle needs to be long enough to reach the muscle of the person you’re injecting.

Can B12 cause skin problems?

Cutaneous manifestations associated with vitamin B12 deficiency are skin hyperpigmentation, vitiligo, angular stomatitis, and hair changes.

Can B12 deficiency cause red spots on skin?

Some people develop skin rashes from vitamin B12 deficiency. Ironically, skin rashes can also occur as a response to supplement treatment for B12 deficiency.

Is there any side effects of B12?

High doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache. Nausea and vomiting. Diarrhea.

Do you keep B12 injections in the fridge?

Store the vials in a cool room. Don’t store them inside a kitchen cabinet or the refrigerator. According to the medical site Drug3K, B12 injections should be stored at a stable temperature of between 59 and 86 degrees Fahrenheit.

How long does B12 rash last?

If you discontinue B12 injections, it may take as long as four months for your rash to clear up.

Can B12 cause skin issues?

Skin lesions associated with vitamin B12 deficiency are skin hyperpigmentation, vitiligo, angular stomatitis, and hair changes. Cutaneous lesions that do not respond to conventional therapy can be an indication of vitamin B12 deficiency. Malabsorption is the most common cause of vitamin B12 deficiency.

What happens if you inject B12 in the wrong place?

Injecting in the wrong area can cause an abscess to form under the skin. To avoid this only inject in the area recommended by your nurse or doctor. Do not inject into a painful or inflamed area. Seek medical advice if this happens.

Do you pinch skin giving subcutaneous injection?

Pinching and pulling gently will pull the subcutaneous tissue away from the muscle. Remove any safety device from the needle. Poke the needle straight into the skin you are pinching. The needle can be inserted at a 90-degree angle (straight in, somewhat like a dart) or at a 45-degree angle.

Does B12 have to be injected intramuscular?

Vitamin B12 shots are the most common way to prevent or treat a deficiency. The injections are prescribed by a doctor and given intramuscularly, or into muscle. Injections are usually given as hydroxocobalamin or cyanocobalamin.

Do you pinch the skin when giving an IM injection?

Insert needle at an 45o angle to the skin. Pinch up on SQ tissue to prevent injecting into muscle. Aspiration before injection is not required.

Does B12 injection have to be in muscle?

Vitamin B12 injections can be administered as an intramuscular or subcutaneous injection. The difference between the two is that intramuscular injections are inserted into the muscle, and subcutaneous injections are inserted just below the skin.

Can too much B12 cause swelling?

Even in high doses, B12 supplements and injections aren’t linked to dangerous side effects. However, B12 may lead to some more mild side effects, such as diarrhea and swelling. B12 injections could also interact with certain medications.

What are the symptoms of vitamin B toxicity?

An overdose of Vitamin B complex usually occurs from the excessive consumption of supplements, The complications that one notices in case of an overdose are skin rashes, insomnia, gastrointestinal problem, Tingling and numbness, Extreme mood swings, and abnormal blood pressure levels.

What should I do after wrong injection?

Call your healthcare provider right away if you have any of these:

  1. Fever of 100.4°F (38°C) or higher, or as directed.
  2. Severe pain at the injection site.
  3. Blistering at the injection site.
  4. Muscle aches.
  5. Upset stomach (nausea), headache, or dizziness.
  6. Skin rash, severe itching, or hives.
  7. Swelling of the lips, tongue, or throat.

What happens if you give a subcutaneous injection wrong?

The most common complication of a subcutaneous injection is pain near the injection site for 1 to 2 days afterward. Pain near the injection site can happen when inserting the needle at the wrong angle, or when it moves slightly during the injection.