What is the indication of trimetazidine?

Trimetazidine is indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Build, train, & validate predictive machine-learning models with structured datasets.

What is the medicine trimetazidine used for?

Trimetazidine is an anti-ischemic agent widely used in the treatment of coronary artery disease.

Is trimetazidine good for the heart?

Trimetazidine has been shown to enhance cardiac function by modulating cardiomyocyte autophagy. Indeed, administration of trimetazidine in diabetic cardiomyopathy rats was shown to enhance cardiomyocyte autophagy and improve cardiac function (Zhang et al., 2016).

What is the action of trimetazidine?

Trimetazidine is a cytoprotective drug that normalizes metabolic disturbances in low-flow ischemia via several—not yet fully understood—mechanisms of action. The best known trimetazidine mechanism of action is its capacity to inhibit β-oxidation of free fatty acid (FFA) [1].

Is trimetazidine used for hypertension?

It was found that trimetazidine complies with several requirements for the effective drug administered to the patients with hypertension associated with ischemic heart disease as it: (a) reduces peripheral resistance and exerts favourable effect on the walls tonus of larger arteries; (b) lowers specifically post- …

Is trimetazidine used for angina?

Trimetazidine is effective in the treatment of stable angina compared with placebo, alone or combined with conventional anti‐anginal agents. Trimetazidine may result in fewer dropouts due to adverse events.

How serious is angina?

Angina is chest pain caused by reduced blood flow to the heart muscles. It’s not usually life threatening, but it’s a warning sign that you could be at risk of a heart attack or stroke. With treatment and healthy lifestyle changes, it’s possible to control angina and reduce the risk of these more serious problems.

How long should trimetazidine be taken?

Usually, TRIMETAZIDINE is prescribed for long-term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor’s consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.

When is the best time to take trimetazidine?

The dose is one tablet of 20mg or 1 ml (20 drops) of oral drop solution of trimetazidine three times a day during meals. The dose is one tablet of 35mg of trimetazidine twice daily during meals.

What is the fastest way to cure angina?

If you need immediate relief from your angina:

  1. Stop, relax, and rest. Lie down if you can.
  2. Take nitroglycerin.
  3. If the pain or discomfort doesn’t stop a few minutes after taking nitroglycerin or if your symptoms become more severe, call 911 or let someone know that you need immediate medical assistance.

Can ECG detect angina?

Diagnosing angina

Your doctor can suspect a diagnosis of angina based on your description of your symptoms, when they appear and your risk factors for coronary artery disease. Your doctor will likely first do an electrocardiogram (ECG) to help determine what additional testing is needed to confirm the diagnosis.

What happens when you stop taking trimetazidine?

Do not stop taking your medication without checking with your healthcare professional. If you stop taking your medication, you may experience a worsening of your condition. This medicine should be taken with or after food.

Which fruit is best for angina?

Fruits such as oranges, cantaloupes and papaya are rich in beta-carotene, potassium, magnesium and fiber. Dark chocolate is good for your heart health.

Which medicine is best for angina?

The most common form of nitrate used to treat angina is nitroglycerin. The nitroglycerin pill is placed under the tongue. Your health care provider might recommend taking a nitrate before activities that typically trigger angina (such as exercise) or on a long-term preventive basis. Aspirin.

What is blood test for angina?

Blood tests check the level of cardiac troponins. Troponin levels can help doctors tell unstable angina from heart attacks. Your doctor may also check levels of certain fats, cholesterol, sugar, and proteins in your blood.

Which drink is best for heart?

6 Drinks to Boost Heart Health

  • Pomegranate juice. According to experts, pomegranates are uniquely healthy fruits for your heart.
  • Coffee. Studies have shown that people who drink 3-5 cups of coffee per day have a significantly lower risk of heart disease, stroke and heart failure.
  • Tea.
  • Tomato juice.
  • Green juice.
  • Smoothies.

What is the first line drug for angina?

Beta-blockers are an appropriate first-line medical treatment to relieve the symptoms of angina. Calcium channel blockers or long-acting nitrates may be appropriate for those who do not tolerate or who have contraindications to beta-blockers.

What is the first aid treatment for angina?

What to do

  1. Instruct the casualty to stop what they are doing and help them to sit down.
  2. Ask if the casualty has any angina medication, like a spray or tablets.
  3. If the pain is still there five minutes after taking the medication, suggest they take a second dose and keep any bystanders away.

Is angina seen on ECG?

Can a chest xray show angina?

A chest x-ray doesn’t diagnose angina, but it may rule out other causes of chest pain. Blood tests — blood tests look for risk factors of heart disease.

Which fruit is best for heart?

Berries are chock full of heart-healthy phytonutrients and soluble fiber. Try blueberries, strawberries, blackberries or raspberries in cereal or yogurt. Seeds. Flaxseeds contain omega-3 fatty acids, fiber and phytoestogens to boost heart health.

What food make heart stronger?

What are the best foods for heart health?

  • Asparagus. Asparagus is a natural source of folate, which helps to prevent an amino acid called homocysteine from building up in the body.
  • Beans, peas, chickpeas, and lentils.
  • Berries.
  • Broccoli.
  • Chia seeds and flaxseeds.
  • Dark chocolate.
  • Coffee.
  • Fish high in omega-3s.

How can I reduce angina immediately?

Which tablet is best for chest pain?

Nitroglycerin — usually taken as a tablet under the tongue — relaxes heart arteries, so blood can flow more easily through the narrowed spaces. Some blood pressure medicines also relax and widen blood vessels. Aspirin.

Is walking good for angina?

What type of exercise should I do? Aerobic exercises will provide the most benefits because they make your heart beat faster and you breathe more quickly. You could try walking, cycling or a living room workout at a level that suits you.