Is doxofylline FDA approved?
In February 2014, the US FDA granted an orphan drug designation to doxofylline for the treatment of bronchiectasis following the submission of an application by Alitair Pharmaceuticals, in May 2013 .
How many days should I take doxofylline?
After repeated administrations doxofylline reaches the steady-state in about 4 days. Following oral administration of 400 mg doxofylline twice daily for 5 days in adults with chronic bronchitis, the peak plasma concentrations (Cmax) at steady state ranged from 5.78 to 20.76 mcg/mL.
What is the indication of doxofylline?
Doxofylline is indicated for the treatment of bronchial asthma, pulmonary disease with spastic bronchial component and Chronic Obstructive Pulmonary Disease (COPD). This product is contraindicated in individuals who have shown hypersensitivity to its components.
What is the therapeutic class of doxofylline?
R03DA11 – doxofylline ; Belongs to the class of xanthines. Used in the systemic treatment of obstructive airway diseases.
Is Doxofylline 400 mg safe?
Studies in both animals as well as in human adults have shown doxofylline to be safe and effective.
Is Doxofylline safe for heart patients?
Do not take DOXOFYLLINE if you have low blood pressure or had a heart attack. DOXOFYLLINE should be used with caution in congestive heart failure patients as these patients have slow drug clearance leading to high blood levels even after stopping treatment with DOXOFYLLINE.
When is the best time to take Doxofylline?
You have been prescribed Doxofylline for prevention and treatment of asthma and chronic obstructive pulmonary disease (COPD). It should be taken at the same time each day, preferably in the evening after food. It does not work right away and should not be used to relieve sudden breathing problems.
What are the side effects of Doxofylline?
Doxofylline may cause any of the following side effects: headache, fast and irregular heartbeat, nausea, vomiting, stomach pain, irritability, difficulty sleeping, and fast and irregular breathing. Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
What is the action of Doxofylline?
Doxofylline is a xanthine molecule having both bronchodilator and anti-inflammatory activity with an improved therapeutic window over conventional xanthines such as theophylline.
Is doxofylline safe for heart patients?
Doxofylline: a new generation xanthine bronchodilator devoid of major cardiovascular adverse effects.
Does doxofylline increase blood pressure?
In the anesthetized cat, doxofylline (1-30 mg/kg. i.v.) did not affect the diastolic blood pressure, but the heart rate increased slightly at a dose of 30 mg/kg i.v. On the contrary, theophylline induced a marked dose-dependent hypotensive and positive chronotropic effect.
Does Doxofylline increase blood pressure?
Is Doxofylline used for cough?
DOXOFYLLINE is a bronchodilator and also possess antitussive (cough suppressant) properties that are used to treat symptoms of asthma and chronic obstructive pulmonary diseases (COPD). DOXOFYLLINE works by relaxing muscles and widening the airways of the lungs, especially in asthma and COPD patients.
Does Doxofylline increased heart rate?
What is the side effect of Doxofylline?
Does doxofylline increased heart rate?
Is Doxofylline good for dry cough?
DOXOFYLLINE works by relaxing muscles and widening the airways of the lungs, especially in asthma and COPD patients. Additionally, DOXOFYLLINE helps in suppressing cough and makes breathing easier by opening airways.
Does doxofylline reduce cough?
What is the best drug for dry cough?
Medical treatment for a dry cough
- pseudoephedrine (Sudafed)
- oxymetazoline (Afrin)
- phenylephrine (Neo-Synephrine)
What are the 4 types of cough?
The four main types of coughs are: wet, dry, paroxysmal and croup. Most coughs do go away on their own. Home remedies and over-the-counter cough medicines can help relieve symptoms.
- Wet cough. This kind of cough sounds wet because it brings up mucus.
- Dry cough.
- Paroxysmal cough.
- Croup cough.
What would a doctor prescribe for a cough?
Prescription cough medicines
Consider benzonatate (Tessalon) capsules. Benzonatate is a prescription, non-narcotic antitussive medication that numbs the airways, the air sacs (alveoli) in the lungs, and the lining of the lungs (pleura). It’s FDA-approved for adults and children over 10 years old.
What kind of cough is pneumonia?
A cough that produces green, yellow, or bloody mucus is the most common symptom of pneumonia. Other symptoms include fever, shaking chills, shortness of breath, low energy, and extreme tiredness. Pneumonia can often be diagnosed with a thorough history and physical exam.
When a cough is serious?
Call your doctor if your cough (or your child’s cough) doesn’t go away after a few weeks or if it also involves any one of these: Coughing up thick, greenish-yellow phlegm. Wheezing. Experiencing a fever.
Which tablet is best for cough?
What is the best medicine for dry cough?
|Best medicine for dry cough|
|Mucinex (guaifenesin)||Expectorant||One 1200 mg extended-release tablet taken every 12 hours|
|Sudafed (pseudoephedrine)||Nasal decongestant||One 30 mg tablet every four to six hours|
What is the best antibiotic to treat pneumonia?
In otherwise uncomplicated pneumonia, azithromycin is the initial drug of choice, as it covers most of the potential etiologic agents, including Mycoplasma species.