How long can you be on Depakote?

The drugmaker says that clinical trials have not shown valproate to be effective for long-term use in patients with mania. This refers to use longer than three weeks. AbbVie recommends that doctors who give patients Depakote or Depakote ER for extended periods continually evaluate the risks and benefits of the drug.

Can you become dependent on Depakote?

Is Depakote habit-forming? Depakote has no habit-forming potential, but it is not recommended that you discontinue use of the drug before talking with your doctor, as withdrawal symptoms can occur.

Can Depakote be discontinued?

Q: Can I stop taking Depakote at any time? A: Do not stop taking Depakote without first talking to your doctor. Stopping Depakote suddenly can cause serious problems, including seizures that do not stop (also known as “status epilepticus”).

Is Depakote a serious medication?

The medication Depakote (divalproex sodium) is an anticonvulsant. Doctors prescribe it to treat seizure disorders and to prevent migraine headaches. People also use it to manage the manic phase of bipolar disorder. Depakote side effects can be serious and sometimes fatal.

Is there a lawsuit against Depakote?

Over the years, millions of patients have taken the medication. Unfortunately, Depakote has been linked to serious medical complications such as birth defects. As a result, numerous lawsuits have been filed in the courts.

Can Depakote change your personality?

Divalproex sodium may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you notice any of these side effects, tell your doctor right away.

Can Depakote cause permanent damage?

Yes, it’s possible for Depakote and Depakote ER to cause long-term side effects. Liver damage, including liver failure, has been reported. Pancreatitis (swelling and damage of the pancreas) has also been reported, including in people who’ve taken Depakote for years.

What can you replace Depakote with?


  • Levetiracetam.
  • Carbamazepine.
  • Gabapentin.
  • Topiramate.
  • Clobazam.
  • What is the lawsuit against Depakote?

    Lawsuits alleging birth defects from Depakote typically involve allegations that Abbott Laboratories: Manufactured and sold a defective drug. Failed to adequately research the potential pregnancy risks of Depakote. Failed to provide warnings to consumers and doctors about the potential risk of birth defects from …

    Why was Depakote taken off the market?

    In 1999, Abbott was forced to discontinue a clinical trial of Depakote in the treatment of dementia due to an increased incidence of adverse events, including somnolence, dehydration and anorexia experienced by the elderly study participants administered Depakote.

    What organ is affected by Depakote?

    Depakote side effects include damage to the liver and pancreas. In 2006, the FDA required that the drug’s label feature a black-box warning indicating an increased risk of pancreatitis and liver failure.

    What are signs of Depakote toxicity?

    Key signs and symptoms include: CNS depression, lethargy and encephalopathy, respiratory depression, nausea/vomiting and myoclonus. Laboratory abnormalities are particularly helpful in this case.

    What is the safest mood stabilizer?

    The safest and most efficacious mood stabilizer combinations appear to be the mixtures of anticonvulsants and lithium, particularly valproate plus lithium.

    What is a good substitute for Depakote?

    What is the newest drug for bipolar disorder?

    Caplyta Now Approved for Bipolar Depression in Adults

    • In December 2021, the FDA approved Caplyta (lumateperone) to treat depressive episodes in bipolar 1 or 2 disorder in adults.
    • Caplyta is an oral capsule that you take once a day with or without food.
    • There are many ways to save on Caplyta.

    What drugs worsen bipolar?

    Drugs with a definite propensity to cause manic symptoms include levodopa, corticosteroids and anabolic-androgenic steroids. Antidepressants of the tricyclic and monoamine oxidase inhibitor classes can induce mania in patients with pre-existing bipolar affective disorder.

    Will they ever find a cure for bipolar disorder?

    There is no cure for bipolar disorder, but through behavior therapy and the right combination of mood stabilizers and other bipolar medicines, most people with bipolar disorder can live normal, productive lives and control the illness.

    What is the most severe form of bipolar disorder?

    Types of bipolar disorder

    Bipolar I disorder is the most severe form of the illness. Bipolar II disorder is characterized by predominantly depressive episodes accompanied by occasional hypomanic episodes. Hypomanic episodes are milder than manic episodes but can still impair functioning.

    What is the average lifespan of someone with bipolar disorder?

    The life expectancy for someone with bipolar disorder is approximately 67 years old. A 2021 study researched the effect of bipolar disorder on longevity and found that: risk of death is 2.6 times greater than the general population. the average life span is between 8–12 years shorter than the general population.

    Can bipolar turn into schizophrenia?

    While bipolar disorder cannot develop into schizophrenia, it’s possible to experience symptoms of both. Before you consult a mental health professional, here are a few things you should know about the two conditions.

    What is the number one cause of bipolar disorder?

    Bipolar disorder is widely believed to be the result of chemical imbalances in the brain. The chemicals responsible for controlling the brain’s functions are called neurotransmitters, and include noradrenaline, serotonin and dopamine.

    What is worse than being bipolar?

    Schizophrenia causes symptoms that are more severe than the symptoms of bipolar disorder. People with schizophrenia experience hallucinations and delusions. Hallucinations involve seeing, hearing, tasting, smelling, or feeling things that aren’t there.

    Can bipolar turn into dementia?

    The risk of developing dementia is much higher among people who’ve had bipolar disorder, according to several studies. A 2020 analysis determined that people with bipolar disorder are about three times more likely to develop dementia, while another expansive analysis also found a significantly increased risk.

    Does bipolar get worse as you get older?

    Bipolar may worsen with age or over time if this condition is left untreated. As time goes on, a person may experience episodes that are more severe and more frequent than when symptoms first appeared.

    Is bipolar a disability?

    Bipolar disorder is considered a disability under the ADA, just like blindness or multiple sclerosis. You may also qualify for Social Security benefits if you can’t work.